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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Efforts to detect and investigate key oncogenic mutations have proven valuable to facilitate the appropriate treatment for cancer patients. The establishment of high-throughput, massively parallel "next-generation" sequencing has aided the discovery of many such mutations. To enhance the c...

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Autori principali: Won, Helen H, Scott, Sasinya N, Brannon, A. Rose, Shah, Ronak H, Berger, Michael F
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947962/
https://ncbi.nlm.nih.gov/pubmed/24192750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50710
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