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Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours

Despite the current wealth of sequencing data, one-third of all biochemically characterized metabolic enzymes lack a corresponding gene or protein sequence, and as such can be considered orphan enzymes. They represent a major gap between our molecular and biochemical knowledge, and consequently are...

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Bibliografiske detaljer
Main Authors: Yamada, Takuji, Waller, Alison S, Raes, Jeroen, Zelezniak, Aleksej, Perchat, Nadia, Perret, Alain, Salanoubat, Marcel, Patil, Kiran R, Weissenbach, Jean, Bork, Peer
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377989/
https://ncbi.nlm.nih.gov/pubmed/22569339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.13
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