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Denosumab Treatment for Fibrous Dysplasia
Fibrous dysplasia (FD) is a skeletal disease caused by somatic activating mutations of the cAMP-regulating protein, G(s)α. These mutations lead to replacement of normal bone by proliferative osteogenic precursors, resulting in deformity, fracture, and pain. Medical treatment has been ineffective in...
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| Hlavní autoři: | , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377825/ https://ncbi.nlm.nih.gov/pubmed/22431375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1603 |
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