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Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice

We have reported that, in addition to recapitulating the classical human Gaucher disease (GD1) phenotype, deletion of the glucocerebrosidase (GBA1) gene in mice results in the dysfunction of a diverse population of immune cells. Most of immune-related, non-classical features of GD1, including gammop...

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Detalhes bibliográficos
Main Authors: Yuen, Tony, Iqbal, Jameel, Zhu, Ling-Ling, Sun, Li, Lin, Aiping, Zhao, Hongyu, Liu, Jun, Mistry, Pramod K., Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377787/
https://ncbi.nlm.nih.gov/pubmed/22588172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.05.027
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