Human Umbilical Cord Blood-Derived CD34(+) Cells Reverse Osteoporosis in NOD/SCID Mice by Altering Osteoblastic and Osteoclastic Activities

BACKGROUND: Osteoporosis is a bone disorder associated with loss of bone mineral density and micro architecture. A balance of osteoblasts and osteoclasts activities maintains bone homeostasis. Increased bone loss due to increased osteoclast and decreased osteoblast activities is considered as an und...

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Autors principals: Aggarwal, Reeva, Lu, Jingwei, Kanji, Suman, Joseph, Matthew, Das, Manjusri, Noble, Garrett J., McMichael, Brooke K., Agarwal, Sudha, Hart, Richard T., Sun, Zongyang, Lee, Beth S., Rosol, Thomas J., Jackson, Rebecca, Mao, Hai-Quan, Pompili, Vincent J., Das, Hiranmoy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377665/
https://ncbi.nlm.nih.gov/pubmed/22724005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039365
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