PET Imaging a MPTP-Induced Mouse Model of Parkinson’s Disease Using the Fluoropropyl-Dihydrotetrabenazine Analog [(18)F]-DTBZ (AV-133)

Parkinson’s disease (PD) is characterized by the loss of dopamine-producing neurons in the nigrostriatal system. Numerous researchers in the past have attempted to track the progression of dopaminergic depletion in PD. We applied a quantitative non-invasive PET imaging technique to follow this degen...

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Detalhes bibliográficos
Main Authors: Toomey, James S., Bhatia, Shilpa, Moon, La’Wanda T., Orchard, Elysse A., Tainter, Kerrie H., Lokitz, Stephen J., Terry, Tracee, Mathis, J. Michael, Penman, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377623/
https://ncbi.nlm.nih.gov/pubmed/22723923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039041
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