Tumor Cell Programmed Death Ligand 1-Mediated T Cell Suppression Is Overcome by Coexpression of CD80

Programmed death ligand 1 (PDL1, or B7-H1) is expressed constitutively or is induced by IFN-γ on the cell surface of most human cancer cells and acts as a “molecular shield” by protecting tumor cells from T cell-mediated destruction. Using seven cell lines representing four histologically distinct s...

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Detalhes bibliográficos
Main Authors: Haile, Samuel T., Bosch, Jacobus J., Agu, Nnenna I., Zeender, Annette M., Somasundaram, Preethi, Srivastava, Minu K., Britting, Sabine, Wolf, Julie B., Ksander, Bruce R., Ostrand-Rosenberg, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377446/
https://ncbi.nlm.nih.gov/pubmed/21555531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003682
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