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Annexin A1 attenuates EMT and metastatic potential in breast cancer

Metastasis is the major cause of carcinoma-induced death, but mechanisms involved are poorly understood. Metastasis crucially involves epithelial-to-mesenchymal transition (EMT), causing loss of epithelial polarity. Here we identify Annexin A1 (AnxA1), a protein with important functions in intracell...

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Detalhes bibliográficos
Main Authors: Maschler, Sabine, Gebeshuber, Christoph A, Wiedemann, Eva-Maria, Alacakaptan, Memetcan, Schreiber, Martin, Custic, Ivana, Beug, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377343/
https://ncbi.nlm.nih.gov/pubmed/20821804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000095
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