ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1

Sodium transport via epithelial sodium channels (ENaC) expressed in alveolar epithelial cells (AEC) provides the driving force for removal of fluid from the alveolar space. The membrane-bound channel-activating protease 1 (CAP1/Prss8) activates ENaC in vitro in various expression systems. To study t...

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Main Authors: Planès, Carole, Randrianarison, Nadia H, Charles, Roch-Philippe, Frateschi, Simona, Cluzeaud, Françoise, Vuagniaux, Grégoire, Soler, Paul, Clerici, Christine, Rossier, Bernard C, Hummler, Edith
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377187/
https://ncbi.nlm.nih.gov/pubmed/20043279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.200900050
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