Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice

Mutations in LAMA2 cause a severe form of congenital muscular dystrophy, called MDC1A. Studies in mouse models have shown that transgenic expression of a designed, miniaturized form of the extracellular matrix molecule agrin (‘mini-agrin’) or apoptosis inhibition by either overexpression of Bcl2 or...

Full description

Saved in:
Bibliographic Details
Main Authors: Meinen, Sarina, Lin, Shuo, Thurnherr, Raphael, Erb, Michael, Meier, Thomas, Rüegg, Markus A
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377088/
https://ncbi.nlm.nih.gov/pubmed/21674808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100151
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items