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Tgf-β1 produced by activated CD4(+) T Cells Antagonizes T Cell Surveillance of Tumor Development

TGFβ1 is a regulatory cytokine with a crucial function in the control of T cell tolerance to tumors. Our recent study revealed that T cell-produced TGFβ1 is essential for inhibiting cytotoxic T cell responses to tumors. However, the exact TGFβ1-producing T cell subset required for tumor immune evasi...

詳細記述

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書誌詳細
主要な著者: Donkor, Moses K., Sarkar, Abira, Li, Ming O.
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376999/
https://ncbi.nlm.nih.gov/pubmed/22720237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18481
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