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T cell- but not tumor cell-produced TGF-β1 promotes the development of spontaneous mammary cancer

During their development, tumors acquire multiple capabilities that enable them to proliferate, disseminate and evade immunosurveillance. A putative mechanism is through the production of the cytokine TGF-β1. We showed in our recent studies that T cell-produced TGF-β1 inhibits antitumor T cell respo...

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Bibliographic Details
Main Authors: Sarkar, Abira, Donkor, Moses K., Li, Ming O.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282091/
https://ncbi.nlm.nih.gov/pubmed/22248703
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