IL-33/ST2 axis in innate and acquired immunity to tumors

Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated. Using metastatic breast cancer model we provide evidence that lack of ST2 signaling led to reduced tumor growth and metastasis and enhanced an...

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Autori principali: Jovanovic, Ivan P., Pejnovic, Nada N., Radosavljevic, Gordana D., Arsenijevic, Nebojsa N., Lukic, Miodrag L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376988/
https://ncbi.nlm.nih.gov/pubmed/22720252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18131
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