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IL-33/ST2 axis in innate and acquired immunity to tumors
Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated. Using metastatic breast cancer model we provide evidence that lack of ST2 signaling led to reduced tumor growth and metastasis and enhanced an...
Sparad:
| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376988/ https://ncbi.nlm.nih.gov/pubmed/22720252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18131 |
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