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Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer

Human prostate cancer frequently metastasizes to bone marrow. What defines the cellular and molecular predilection for prostate cancer to metastasize to bone marrow is not well understood. CD4(+)CD25(+) regulatory T (Treg) cells contribute to self-tolerance and tumor immune pathology. We now show th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Ende, Wang, Lin, Dai, Jinlu, Kryczek, Ilona, Wei, Shuang, Vatan, Linda, Altuwaijri, Saleh, Sparwasser, Tim, Wang, Guobin, Keller, Evan T., Zou, Weiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376984/
https://ncbi.nlm.nih.gov/pubmed/22720236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18480
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