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Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer

Human prostate cancer frequently metastasizes to bone marrow. What defines the cellular and molecular predilection for prostate cancer to metastasize to bone marrow is not well understood. CD4(+)CD25(+) regulatory T (Treg) cells contribute to self-tolerance and tumor immune pathology. We now show th...

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Autors principals: Zhao, Ende, Wang, Lin, Dai, Jinlu, Kryczek, Ilona, Wei, Shuang, Vatan, Linda, Altuwaijri, Saleh, Sparwasser, Tim, Wang, Guobin, Keller, Evan T., Zou, Weiping
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376984/
https://ncbi.nlm.nih.gov/pubmed/22720236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18480
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