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CCR5 in cancer immunotherapy: More than an “attractive” receptor for T cells

Despite intensive study, the role of CCR5 in cancer remains elusive. We showed that CCR5 expression by both CD4+ and CD8+ T cells is necessary to boost anti-tumor responses by optimizing helper-dependent CD8+ T cell priming. Our findings could have implications for cancer treatment in patients with...

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Detalhes bibliográficos
Main Authors: González-Martín, Alicia, Mira, Emilia, Mañes, Santos
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376953/
https://ncbi.nlm.nih.gov/pubmed/22720226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.17995
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