Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

Chikungunya virus (CHIKV) and related arboviruses have been responsible for large epidemic outbreaks with serious economic and social impact. The immune mechanisms, which control viral multiplication and dissemination, are not yet known. Here, we studied the antibody response against the CHIKV surfa...

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Autors principals: Kam, Yiu-Wing, Lum, Fok-Moon, Teo, Teck-Hui, Lee, Wendy W L, Simarmata, Diane, Harjanto, Sumitro, Chua, Chong-Long, Chan, Yoke-Fun, Wee, Jin-Kiat, Chow, Angela, Lin, Raymond T P, Leo, Yee-Sin, Le Grand, Roger, Sam, I-Ching, Tong, Joo-Chuan, Roques, Pierre, Wiesmüller, Karl-Heinz, Rénia, Laurent, Rötzschke, Olaf, Ng, Lisa F P
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376860/
https://ncbi.nlm.nih.gov/pubmed/22389221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200213
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