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Progesterone turnover to its 5α-reduced metabolites in the ventral tegmental area of the midbrain is essential for initiating social and affective behavior and progesterone metabolism in female rats

BACKGROUND: Among women and female rodents, progesterone (P) influences social affiliation and affect. These effects may be partly due to formation of its 5α-reduced, 3α-hydroxylated metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP). AIM: To elucidate whether actions of 3α,5α-THP in the midbrain ventr...

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Bibliografski detalji
Glavni autori: Frye, C.A., Paris, J.J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376830/
https://ncbi.nlm.nih.gov/pubmed/21060252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3275/7334
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