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A General Framework for Two-Stage Analysis of Genome-wide Association Studies and Its Application to Case-Control Studies

Two-stage analyses of genome-wide association studies have been proposed as a means to improving power for designs including family-based association and gene-environment interaction testing. In these analyses, all markers are first screened via a statistic that may not be robust to an underlying as...

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Autors principals: Wason, James M.S., Dudbridge, Frank
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376500/
https://ncbi.nlm.nih.gov/pubmed/22560088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.03.007
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