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Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer

HER2-positive breast cancer accounts for 20–30% of all breast cancers and has the second-poorest prognosis among breast cancer subtypes. The approval of trastuzumab in 1998 has significantly improved patients’ outcomes and paved the way for the beginning of advent of targeted approaches in breast ca...

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Detalles Bibliográficos
Main Authors: Vu, Thuy, Claret, Francois X.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Research Foundation 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376449/
https://ncbi.nlm.nih.gov/pubmed/22720269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00062
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