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Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer

HER2-positive breast cancer accounts for 20–30% of all breast cancers and has the second-poorest prognosis among breast cancer subtypes. The approval of trastuzumab in 1998 has significantly improved patients’ outcomes and paved the way for the beginning of advent of targeted approaches in breast ca...

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Bibliografiske detaljer
Main Authors: Vu, Thuy, Claret, Francois X.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376449/
https://ncbi.nlm.nih.gov/pubmed/22720269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00062
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