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Association between BclI polymorphism in the NR3C1 gene and in vitro individual variations in lymphocyte responses to methylprednisolone

AIM: To evaluate the association between the in vitro sensitivity of peripheral blood mononuclear cells (PBMCs) to methylprednisolone (MP) and the presence of genetic polymorphisms involved in glucocorticoid (GC) response. METHODS: In vitro MP inhibition of the proliferation of lymphocytes stimulate...

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Autori principali: Cuzzoni, Eva, De Iudicibus, Sara, Bartoli, Fiora, Ventura, Alessandro, Decorti, Giuliana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376441/
https://ncbi.nlm.nih.gov/pubmed/22008062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04130.x
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