Population pharmacokinetics of ciclosporin in haematopoietic allogeneic stem cell transplantation with emphasis on limited sampling strategy

AIM: To develop a population pharmacokinetic model of ciclosporin (CsA) in haematopoietic allogeneic stem cell transplantation to facilitate a limited sampling strategy to determine systemic exposure (area under the curve [AUC]), in order to optimize CsA therapy in this patient population. METHODS:...

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Bibliographic Details
Main Authors: Wilhelm, Abraham J, de Graaf, Peer, Veldkamp, Agnes I, Janssen, Jeroen J W M, Huijgens, Peter C, Swart, Eleonora L
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376432/
https://ncbi.nlm.nih.gov/pubmed/21988410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04116.x
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