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Contributions of Intracellular Ions to Kv Channel Voltage Sensor Dynamics

Voltage-sensing domains (VSDs) of Kv channels control ionic conductance through coupling of the movement of charged residues in the S4 segment to conformational changes at the cytoplasmic region of the pore domain, that allow K(+) ions to flow. Conformational transitions within the VSD are induced b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goodchild, Samuel J., Fedida, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Research Foundation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376422/
https://ncbi.nlm.nih.gov/pubmed/22719727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00114
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