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Contributions of Intracellular Ions to Kv Channel Voltage Sensor Dynamics

Voltage-sensing domains (VSDs) of Kv channels control ionic conductance through coupling of the movement of charged residues in the S4 segment to conformational changes at the cytoplasmic region of the pore domain, that allow K(+) ions to flow. Conformational transitions within the VSD are induced b...

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Bibliografske podrobnosti
Main Authors: Goodchild, Samuel J., Fedida, David
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376422/
https://ncbi.nlm.nih.gov/pubmed/22719727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00114
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