MLH1 promoter hypermethylation in the analytical algorithm of Lynch syndrome: a cost-effectiveness study

The analytical algorithm of Lynch syndrome (LS) is increasingly complex. BRAF V600E mutation and MLH1 promoter hypermethylation have been proposed as a screening tool for the identification of LS. The aim of this study was to assess the clinical usefulness and cost-effectiveness of both somatic alte...

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Bibliografiset tiedot
Päätekijät: Gausachs, Mireia, Mur, Pilar, Corral, Julieta, Pineda, Marta, González, Sara, Benito, Llúcia, Menéndez, Mireia, Espinàs, Josep Alfons, Brunet, Joan, Iniesta, María Dolores, Gruber, Stephen B, Lázaro, Conxi, Blanco, Ignacio, Capellá, Gabriel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376264/
https://ncbi.nlm.nih.gov/pubmed/22274583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.277
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