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Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48(Cre/+).LSL-Kras(G12D/+) mice

Pancreatic cancer is the one of most common causes of cancer deaths and has the worst prognosis. Clinical observational studies suggest that statins may reduce the risk of pancreatic cancer. The chemopreventive efficacy of the statin atorvastatin (Lipitor®) and the role of the phosphatidyl-inositol...

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Bibliografiske detaljer
Main Authors: Mohammed, Altaf, Qian, Li, Janakiram, Naveena B., Lightfoot, Stan, Steele, Vernon E., Rao, Chinthalapally V.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376252/
https://ncbi.nlm.nih.gov/pubmed/22287227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27456
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