MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing

Transposable elements (TEs) and DNA repeats are commonly targeted by DNA and histone methylation to achieve epigenetic gene silencing. We isolated mutations in two Arabidopsis genes, AtMORC1 and AtMORC6, which cause de-repression of DNA-methylated genes and TEs, but no losses of DNA or histone methy...

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Hauptverfasser: Moissiard, Guillaume, Cokus, Shawn J., Cary, Joshua, Feng, Suhua, Billi, Allison C., Stroud, Hume, Husmann, Dylan, Zhan, Ye, Lajoie, Bryan R., McCord, Rachel Patton, Hale, Christopher J., Feng, Wei, Michaels, Scott D., Frand, Alison R., Pellegrini, Matteo, Dekker, Job, Kim, John K., Jacobsen, Steve
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376212/
https://ncbi.nlm.nih.gov/pubmed/22555433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1221472
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