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DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues

Whole-genome copy number analysis platforms, such as array comparative genomic hybridization (aCGH) and single nucleotide polymorphism (SNP) arrays, are transformative research discovery tools. In cancer, the identification of genomic aberrations with these approaches has generated important diagnos...

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Detalhes bibliográficos
Main Authors: Craig, Justin M., Vena, Natalie, Ramkissoon, Shakti, Idbaih, Ahmed, Fouse, Shaun D., Ozek, Memet, Sav, Aydin, Hill, D. Ashley, Margraf, Linda R., Eberhart, Charles G., Kieran, Mark W., Norden, Andrew D., Wen, Patrick Y., Loda, Massimo, Santagata, Sandro, Ligon, Keith L., Ligon, Azra H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376148/
https://ncbi.nlm.nih.gov/pubmed/22719973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038881
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