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Withaferin A Alters Intermediate Filament Organization, Cell Shape and Behavior

Withaferin A (WFA) is a steroidal lactone present in Withania somnifera which has been shown in vitro to bind to the intermediate filament protein, vimentin. Based upon its affinity for vimentin, it has been proposed that WFA can be used as an anti-tumor agent to target metastatic cells which up-reg...

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מידע ביבליוגרפי
Main Authors: Grin, Boris, Mahammad, Saleemulla, Wedig, Tatjana, Cleland, Megan M., Tsai, Lester, Herrmann, Harald, Goldman, Robert D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376126/
https://ncbi.nlm.nih.gov/pubmed/22720028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039065
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