Chargement en cours...

A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands

Target selective drugs, such as dopamine receptor (DR) subtype selective ligands, are developed for enhanced therapeutics and reduced side effects. In silico methods have been explored for searching DR selective ligands, but encountered difficulties associated with high subtype similarity and ligand...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Jingxian, Han, Bucong, Wei, Xiaona, Tan, Chunyan, Chen, Yuzong, Jiang, Yuyang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376116/
https://ncbi.nlm.nih.gov/pubmed/22720033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039076
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!