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Fluorescent Protein–Labeled Glucocorticoid Receptor alpha Isoform Trafficking in Cultured Human Trabecular Meshwork Cells

PURPOSE. To characterize the roles of the cytoskeleton and heat shock protein 90 (HSP90) in steroid-induced glucocorticoid receptor alpha (GRα) translocation in cultured human trabecular meshwork cells. METHODS. Stably transfected red fluorescent protein (RFP)-GRα NTM5 cell lines were developed. Nuc...

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Detalhes bibliográficos
Main Authors: Dibas, Adnan, Jiang, Ming, Fudala, Rafal, Gryczynski, Ignacy, Gryczynski, Zygmunt, Clark, Abbot F., Yorio, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376074/
https://ncbi.nlm.nih.gov/pubmed/22447868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8331
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