Positron Emission Tomography Imaging of Tumor Angiogenesis with a (66)Ga-Labeled Monoclonal Antibody

The goal of this study was to develop a (66)Ga-based positron emission tomography (PET) tracer for non-invasive imaging of CD105 expression during tumor angiogenesis, a hallmark of cancer. (66)Ga was produced using a cyclotron with (nat)Zn or isotopically enriched (66)Zn targets. TRC105, a chimeric...

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Bibliographische Detailangaben
Hauptverfasser: Engle, Jonathan W., Hong, Hao, Zhang, Yin, Valdovinos, Hector F., Myklejord, Duane V., Barnhart, Todd E., Theuer, Charles P., Nickles, Robert J., Cai, Weibo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375902/
https://ncbi.nlm.nih.gov/pubmed/22519890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300019c
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