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The high spontaneous mutation rate: Is it a health risk?

The human mutation rate for base substitutions is much higher in males than in females and increases with paternal age. This effect is mainly, if not entirely, due to the large number of cell divisions in the male germ line. The mutation-rate increase is considerably greater than expected if the mut...

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Detalles Bibliográficos
Autor principal: Crow, James F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC33757/
https://ncbi.nlm.nih.gov/pubmed/9237985
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