Spontaneous mutation rate in retinoblastoma.
A novel approach was used to estimate the in vivo mutation rate of the retinoblastoma gene. A mathematical formula can be used to calculate the probability of neoplasia induced by one or more mutations in a population of dividing cells. This formula can then be applied to epidemiological data on her...
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| Publicado no: | J Clin Pathol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC502505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2380395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.43.6.496 |
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