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In Vivo and In Vitro Effects of a HIF-1α Inhibitor, RX-0047
HIF-1α plays a major role in activating gene transcription and is important for maintaining homeostasis under hypoxic conditions. Since tumors are often in a hypoxic state, HIF-1α is a potential target for the development of novel cancer therapeutics. This study was performed to determine the antitu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375689/ https://ncbi.nlm.nih.gov/pubmed/18275063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21681 |
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