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Studies on the Synthesis of Reidispongiolide A: Stereoselective Synthesis of the C(22)-C(36) Fragment

A highly stereoselective synthesis of the C(22)-C(36) fragment 2 of reidispongiolide A is described. This synthesis features the highly stereoselective mismatched double asymmetric crotylboration reaction of the aldehyde derived from 5 and the new chiral reagent (S)-(E)-7 that provides 12 with >1...

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Autors principals: Ying, Maben, Roush, William R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375686/
https://ncbi.nlm.nih.gov/pubmed/22711935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2011.10.029
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