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Therapeutic siRNA: Principles, Challenges, and Strategies

RNA interference (RNAi) is a remarkable endogenous regulatory pathway that can bring about sequence-specific gene silencing. If harnessed effectively, RNAi could result in a potent targeted therapeutic modality with applications ranging from viral diseases to cancer. The major barrier to realizing t...

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Detalhes bibliográficos
Main Authors: Gavrilov, Kseniya, Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: YJBM 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375670/
https://ncbi.nlm.nih.gov/pubmed/22737048
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