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Distinct Properties of Glycine Receptor β+/α− Interface: UNAMBIGUOUSLY CHARACTERIZING HETEROMERIC INTERFACE RECONSTITUTED IN HOMOMERIC PROTEIN

The glycine receptor (GlyR) exists either in homomeric α or heteromeric αβ forms. Its agonists bind at extracellular subunit interfaces. Unlike subunit interfaces from the homomeric α GlyR, subunit interfaces from the heteromeric αβ GlyR have not been characterized unambiguously because of the exist...

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Autors principals: Shan, Qiang, Han, Lu, Lynch, Joseph W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375546/
https://ncbi.nlm.nih.gov/pubmed/22535951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337741
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