PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-β3 (PLC-β3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-β3 and Somatostatin Receptors

Phospholipase C-β (PLC-β) is a key molecule in G protein-coupled receptor (GPCR)-mediated signaling. Many studies have shown that the four PLC-β subtypes have different physiological functions despite their similar structures. Because the PLC-β subtypes possess different PDZ-binding motifs, they hav...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Jung Kuk, Kwon, Ohman, Kim, Jinho, Kim, Eung-Kyun, Park, Hye Kyung, Lee, Ji Eun, Kim, Kyung Lock, Choi, Jung Woong, Lim, Seyoung, Seok, Heon, Lee-Kwon, Whaseon, Choi, Jang Hyun, Kang, Byoung Heon, Kim, Sanguk, Ryu, Sung Ho, Suh, Pann-Ghill
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375525/
https://ncbi.nlm.nih.gov/pubmed/22528496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337865
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