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Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent

Calcific aortic valve disease (CAVD) results in impaired function through the inability of valves to fully open and close, but the causes of this pathology are unknown. Stiffening of the aorta is associated with CAVD and results in exposing the aortic valves to greater mechanical strain. Transformin...

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Библиографические подробности
Главные авторы: Fisher, Charles I., Chen, Joseph, Merryman, W. David
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375394/
https://ncbi.nlm.nih.gov/pubmed/22307683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0377-8
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