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Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent

Calcific aortic valve disease (CAVD) results in impaired function through the inability of valves to fully open and close, but the causes of this pathology are unknown. Stiffening of the aorta is associated with CAVD and results in exposing the aortic valves to greater mechanical strain. Transformin...

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Detalhes bibliográficos
Main Authors: Fisher, Charles I., Chen, Joseph, Merryman, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375394/
https://ncbi.nlm.nih.gov/pubmed/22307683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0377-8
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