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Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent

Calcific aortic valve disease (CAVD) results in impaired function through the inability of valves to fully open and close, but the causes of this pathology are unknown. Stiffening of the aorta is associated with CAVD and results in exposing the aortic valves to greater mechanical strain. Transformin...

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Bibliografische gegevens
Hoofdauteurs: Fisher, Charles I., Chen, Joseph, Merryman, W. David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375394/
https://ncbi.nlm.nih.gov/pubmed/22307683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0377-8
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