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Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent

Calcific aortic valve disease (CAVD) results in impaired function through the inability of valves to fully open and close, but the causes of this pathology are unknown. Stiffening of the aorta is associated with CAVD and results in exposing the aortic valves to greater mechanical strain. Transformin...

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Détails bibliographiques
Auteurs principaux: Fisher, Charles I., Chen, Joseph, Merryman, W. David
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375394/
https://ncbi.nlm.nih.gov/pubmed/22307683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0377-8
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