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Opposing Regulation of PROX1 by Interleukin-3 Receptor and NOTCH Directs Differential Host Cell Fate Reprogramming by Kaposi Sarcoma Herpes Virus

Lymphatic endothelial cells (LECs) are differentiated from blood vascular endothelial cells (BECs) during embryogenesis and this physiological cell fate specification is controlled by PROX1, the master regulator for lymphatic development. When Kaposi sarcoma herpes virus (KSHV) infects host cells, i...

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Main Authors: Yoo, Jaehyuk, Lee, Ha Neul, Choi, Inho, Choi, Dongwon, Chung, Hee Kyoung, Kim, Kyu Eui, Lee, Sunju, Aguilar, Berenice, Kang, Jinjoo, Park, Eunkyung, Lee, Yong Suk, Maeng, Yong-Sun, Kim, Nam Yoon, Koh, Chester J., Hong, Young-Kwon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375311/
https://ncbi.nlm.nih.gov/pubmed/22719258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002770
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