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Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
Cells respond to defects in mitochondrial function by activating signaling pathways that restore homeostasis. The mitochondrial peptide exporter HAF-1 and the bZip transcription factor ATFS-1 represent one stress response pathway that regulates the transcription of mitochondrial chaperone genes duri...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375257/ https://ncbi.nlm.nih.gov/pubmed/22719267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002760 |
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