Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice

Poly(ADP-ribose) polymerase (PARP) activation has been implicated in the pathogenesis of diabetic complications, including nephropathy and peripheral neuropathy. This study aimed at evaluating the manifestations of both complications in diabetic Akita mice, a model of Type 1 (insulin-dependent) diab...

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Autors principals: DREL, VIKTOR R., PACHER, PAL, STAVNIICHUK, ROMAN, XU, WEIZHENG, ZHANG, JIE, KUCHMEROVSKA, TAMARA M., SLUSHER, BARBARA, OBROSOVA, IRINA G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375175/
https://ncbi.nlm.nih.gov/pubmed/21617845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2011.709
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