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The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning

Nitric oxide (NO)-dependent soluble guanylate cyclase (sGC) activation is an important component of cardiac signal transduction pathways, including the cardioprotective signaling cascade induced by ischemic preconditioning (IPC). The sGCα subunit, which binds to the common sGCβ1 subunit, exists in t...

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書誌詳細
主要な著者: Sips, Patrick Y., Brouckaert, Peter, Ichinose, Fumito
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375061/
https://ncbi.nlm.nih.gov/pubmed/21394564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0167-y
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