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The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning

Nitric oxide (NO)-dependent soluble guanylate cyclase (sGC) activation is an important component of cardiac signal transduction pathways, including the cardioprotective signaling cascade induced by ischemic preconditioning (IPC). The sGCα subunit, which binds to the common sGCβ1 subunit, exists in t...

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Bibliografische gegevens
Hoofdauteurs: Sips, Patrick Y., Brouckaert, Peter, Ichinose, Fumito
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375061/
https://ncbi.nlm.nih.gov/pubmed/21394564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0167-y
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