Gender-Specific Modulation of the Response to Arterial Injury by Soluble Guanylate Cyclase α1

OBJECTIVE: Soluble guanylate cyclase (sGC), a heterodimer composed of α and β subunits, synthesizes cGMP in response to nitric oxide (NO). NO modulates vascular tone and structure but the relative contributions of cGMP-dependent versus cGMP-independent mechanisms remain uncertain. We studied the res...

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Main Authors: Vermeersch, Pieter, Buys, Emmanuel, Sips, Patrick, Pokreisz, Peter, Marsboom, Glenn, Gillijns, Hilde, Pellens, Marijke, Dewerchin, Mieke, Bloch, Kenneth D, Brouckaert, Peter, Janssens, Stefan
Format: Artigo
Language:Inglês
Published: Bentham Open 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743853/
https://ncbi.nlm.nih.gov/pubmed/19771174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874192400903010098
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