Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1

BACKGROUND: Humanized mice generate a lymphoid system of human origin subsequent to transplantation of human CD34+ cells and thus are highly susceptible to HIV infection. Here we examined the efficacy of antiretroviral treatment (ART) when added to food pellets, and of long-acting (LA) antiretrovira...

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Main Authors: Nischang, Marc, Sutmuller, Roger, Gers-Huber, Gustavo, Audigé, Annette, Li, Duo, Rochat, Mary-Aude, Baenziger, Stefan, Hofer, Ursula, Schlaepfer, Erika, Regenass, Stephan, Amssoms, Katie, Stoops, Bart, Van Cauwenberge, Anja, Boden, Daniel, Kraus, Guenter, Speck, Roberto F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374767/
https://ncbi.nlm.nih.gov/pubmed/22719966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038853
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